Thorne Magnesium Bisglycinate Review

A gentle, well-absorbed magnesium powder from a practitioner-favorite brand, useful for relaxation and sleep.
By Health by Research editors | Independent review | Last updated August 2026
Thorne Magnesium Bisglycinate
Thorne Magnesium Bisglycinate: independent, evidence-based review

Editorial note: We review supplements independently. We are not affiliated with Thorne and we do not earn a commission from this review. Our score reflects the product’s ingredients and the evidence behind them. These statements have not been evaluated by the FDA.

What it isMagnesium bisglycinate powder
Best forRelaxation, muscle comfort, and winding down
Typical priceAround 30 to 42 dollars for 60 servings
Keep in mindPowder only, and pricier than basic forms
Our rating
4.5 / 5 ★★★★½

One of the cleaner magnesium options on the market, in a gentle chelated form that is easy on the stomach. It is a strong choice for relaxation and sleep support, with price and powder-only format the main trade-offs.

Where to buy: Thorne ›

What we like

  • Chelated bisglycinate is gentle and well absorbed
  • NSF Certified for Sport and rigorously tested
  • No unnecessary fillers
  • Trusted by many clinicians

Keep in mind

  • Powder only, so you need to mix it
  • More expensive than magnesium oxide or citrate
  • Effects on sleep are supportive, not dramatic

What it is

Thorne Magnesium Bisglycinate is a magnesium powder using the glycinate form, which is chelated to an amino acid for gentle absorption. Thorne is a practitioner-focused brand known for tight quality control and third-party testing.

The evidence

Magnesium supports hundreds of processes in the body, and many adults fall short of the recommended intake. The glycinate form is a sensible pick for relaxation and sleep because it is well tolerated and less likely to cause the loose stools that magnesium oxide can. The sleep benefit is real but modest and works best when you are genuinely low in magnesium.

Who it is for

A good option if you want a gentle, high-quality magnesium for evening use and you do not mind mixing a powder. If you prefer capsules or a lower price, other glycinate products will also do the job.

How we researched this

  • We reviewed the product’s published ingredients, dose, and third-party testing claims.
  • We weighed the human evidence for those ingredients, not marketing language.
  • We have no financial relationship with Thorne, and we note trade-offs honestly.

Frequently asked questions

Is glycinate better than other forms?

For relaxation and sleep, glycinate is a good choice because it is gentle and well absorbed. Citrate is fine too but is more likely to loosen stools.

Can I take it every night?

Nightly use is common and generally well tolerated, but check with your clinician if you have kidney issues.

This review is for general information and is not medical advice. Supplements are not intended to diagnose, treat, cure, or prevent any disease, and these statements have not been evaluated by the FDA. Talk with a qualified clinician before starting any supplement.

Questions & Answers

Common questions we get, answered by the Health by Research editors. Have one of your own? Leave a comment below and we will reply.

Is bisglycinate the same thing as glycinate?

Yes. Magnesium bisglycinate and magnesium glycinate are the same chelated form, and the labels are used interchangeably. It absorbs well and is gentle on the stomach.

Why does a brand like this cost more than a store brand?

You are mostly paying for third-party testing and tighter quality control. Whether that premium is worth it is a personal call, since the magnesium form itself is the same.

Can I take it with my other supplements?

Generally yes. Very high doses of zinc or calcium taken at the exact same time can compete for absorption, so spacing them out by a couple of hours is a simple fix.

References and Further Reading

How we researched this: Our editorial team reviewed current clinical research and guidance from independent health authorities before writing and reviewing this article. You can verify the science yourself through the sources below.

  1. Peer-reviewed research on thorne magnesium bisglycinate (PubMed, U.S. National Library of Medicine)
  2. Magnesium Fact Sheet (NIH Office of Dietary Supplements)
  3. Academic studies on thorne magnesium bisglycinate (Google Scholar)

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